Tuesday, December 24, 2019

Advantages And Disadvantages Of Traditional Economy

The economic system, traditional economy, which is the first and the oldest system appears from the ancient age of human beings. The main production is hunting, gathering, fishing, and agriculture. Its characteristics consist of making economic decisions by the guides from experiences of the elders, producing goods for what people need, and the most unique thing is that this system has no currency (Kimberly Amadeo, 2017). So how do merchandises or customers buy something such as bread or meat? The way to get the goods is that people exchange what they have, which called barter. In fact, traditional economy has some disadvantages and there are only a few countries and indigenous tribes applying this system in the world at the present. They†¦show more content†¦The last disadvantage is that people only produce for what they basically need. Their daily products depend on fishing, hunting, and agriculture; but once the winter comes, there is no way to grow foods, or the animals immigrate every year that makes hunting and fishing impossible. The problem is that they produce limitedly, which means no leftovers. It is due to the fact that people reserve foods for winters; however, they cannot create wealth and their life standard just stays in a low range because there are only a few leftovers. Benefits of Traditional Economy Once again, people only produce goods and services which are essential for survival. This is also an advantage which resources are not wasted while producing goods and services. For example, there are 100 villagers and each of them needs 2kg of fish. Then the fishers must catch at least 200kg of fish. If they cannot consume more than 200kg, then those reserve fishes will be spoiled. Also, people in traditional economy know exactly what their roles or jobs are, which causing no unemployment because they will do a particular job based on their abilities and skills. Additionally, they can trade their products when doing their job to get other products. But if they are unsatisfied of their job, they can find another one instead of protesting. This because they know theShow MoreRelatedMarket Economy988 Words   |  4 PagesPrinciples Practices, one of the disadvantages is â€Å"that it does not provide for the basic needs of everyone in the society.† That is true, but with the assistance from some government services such as Social Security and Medicare, the people will be helped and still remain free to purchase and buy what they want. Another disadvantage that is stated is the possibility of economic failure. The economic could fail if there is not enough competition. In a mixed market economy, the government helps preventRead MoreHistory Of New Zealand Of ficial Career Education Policy1261 Words   |  6 PagesCallanan, and Godschalk (2000), career has a connection with a person’s work experience during a progress of their life (as cited in Porter, 2005). Apart from career itself, we are also aware of both career concepts which is called a traditional and contemporary career. Traditional career is seen as a predictable and secure career, where its hierarchy in the organisation structure was rigid and runs on the stable environment while contemporary career likely tends to be more unpredictable, dynamic and vulnerableRead MoreThe Four Main Economic Systems and Their Application in South Africa1426 Words   |  6 Pagesfour main economic systems are: Traditional, Command, Market and Mixed South Africa has come a long way since the days of apartheid, from being a country living within sanctions to evolving to a mixed economy. It has become too diverse that citizens are liberated into certain economic activities of their choice. Everyone is entitled to their own private freedom, combined with centralized with economic planning and government regulation. Traditional Economy The traditional system is based on ancient methodsRead MoreTourism During The Middle East Business News886 Words   |  4 Pagesdiscovery of the oil the economy of the UAE was dependent on fishing and pearl trade. The people were busy in farming dates, breeding camels and goats.Since the discovery of the oil in 1966, the country’s economy and society have changed considerably. Discovery of the oil boosted the economy and throughout 25 years the UAE has developed high living standards. The oil discovery attracted many foreigners to work in the UAE. Recognizing that the oil , the source that affects the economy, may soon be exhaustedRead MoreThe Benefits Of The Sharing Economy1105 Words   |  5 PagesThe sharing economy is a developing, remarkably flexible economic network that allows people to borrow or rent assets, such as machinery, services, and skills, with one another. The sharing economy is utilized most often when the price of the resource in question is exceptionally high due to the fact that these resources will be shared at a significantly lower cost than retail arrangements. And although humans have shared the use of resources with one another for thousands of years, the growth ofRead MoreTelecommuting1277 Words   |  6 PagesManagement with emphasis in Human Resources Management. Because of the slow economy management want to institute telecommuting and my presentation will focus on the advantages and disadvantages of telecommuting All of us some time or another have had the desire to stay at home and work. I would like to know who would be interested in staying home and working in order to save. I know I would love that because at home has advantages like spending time with my family and being my own boss. Furthermore, thisRead MoreAdvantages and Disadvantages of being a EU member1102 Words   |  5 Pages Advantages vs. Disadvantages of Being an EU Member The European Union purpose is to eliminate barriers for the movement of materials, labor and goods on the continent. This has its advantages and disadvantages for the member state. Some claim there are more advantages than disadvantages, according to the Academic Study in the UK EU has created a more peaceful and stable way of market. The EU was created after the second world war, the plan was to work with economically independent countriesRead MoreImpact Of Online Shopping On Businesses1439 Words   |  6 Pagesinternet shopping . These statistics will significantly affect the work place with people losing their jobs which can be blamed for the popularity of online shopping. This brings rise to other concerns which should be considered including advantages and disadvantages of online shopping, the legislation regulating its use and the economic, ethical and environmental impacts associated with online shopping. Introduction: The issue chosen that is experiencing a strong growth amongst AustralianRead MoreGlobalization Effects on Jamaica and Thailand Essay836 Words   |  4 Pages For both countries globalization has had both advantages and disadvantages. Tourisms Effect on Jamaica Globalization through tourism has had a significant effect on Jamaica. Originally, tourism was intended to profit the country by tourist spending. It was believed the economy would grow from an increase in job availability. Also, the conjecture of most Jamaicans was the hotels generated tourist spending which provided a growing economy. Unfortunately, what was intended to be the mainRead MoreHow Electric Vehicles Can Reduce Greenhouse Gas Emissions900 Words   |  4 Pagesand are considered as a revolutionary innovation designed to protect the earth from the damaging effects of global warming, as they work on the electricity supplying the integrated rechargeable battery that can be easily recharged. Compared to traditional means of transport, electric vehicles seem to be more viable and environmentally friendly because they do not need oil or other fossil fuels as an energy source but the high cost of such a car and other important issues of exploitation discussed

Monday, December 16, 2019

Frequent Shopper Program Free Essays

Kudler Fine Foods (KFF) is a local upscale specialty food store that is committed to providing customers with the finest selection of specialty foods. In addition, KFF would like to reward their customers for their loyalty by incorporating a frequent shopper program. KFF is planning on developing a system that tracks customer purchases and awards loyalty points for redemption. We will write a custom essay sample on Frequent Shopper Program or any similar topic only for you Order Now The system will assist KFF in satisfying their most valued customers. Smith Systems Consulting Firm has been contracted for the development of the system. Smith Systems Consulting has been serving clients since 1994 with high value web and business application services. In this proposal, Smith Systems consulting will propose two alternative methods for completing the frequent shopper application. The advantages and disadvantages for each method and how the firm would conduct testing for each development method will be discussed. Regardless of which method is used, most software process models, follow a similar set of phases and activities. The difference between models is the order and frequency of the phases. The specific parts of the software process are presented below: 1. Inception – Software product is created and defined. 2. Planning – Resources, schedule, and cost are determined. 3. Requirements Analysis – Specify what the application must do. 4. Design – Specify the parts and how they fit 5. Implementation – Write the code 6. Testing – Execute the application with input test data 7. Maintenance – Repair defects and add capability (TechTarget, 2014) The first model that will be proposed is the â€Å"waterfall† process. The â€Å"waterfall† process is the oldest software process model and despite its weaknesses, it is still in widespread use today. The waterfall process requires following the phases in a sequential order where the output for one phase is used as the input for the next. The next phase in the process is not started until the previous one has been completed, although a small overlap between phases is accepted. Two advantages and disadvantages of using this model relative to the frequent shopper program will be discussed. The first advantage is the practicality of the process. We have been using this process for many years and have a great deal of experience with it. All individuals involved have and understanding of the process and its execution. The second advantage is the process is simple and easy to use. The criteria of each phase are set and completed sequentially. The order of execution is easy for everyone to comprehend. There is no question on what needs to be completed before the next phase can begin. The first disadvantage is that requirements need to be known up front. KFF currently has a broad range of requirements and every detail is not known. As the project progresses, more details may become known; which could cause the project to be stopped and re-imagined. The second disadvantage is that there is no feedback of the system by stakeholders until after the testing phase. KFF has no way of knowing if the program meets their requirements because the â€Å"waterfall† process does not facilitate intermediate versions. The second method that will be proposed is the agile methodology. The agile methodology proposes alternatives to traditional project management. Agile development focuses on keeping code simple, testing often, and delivering functional bits of the application as soon as they are ready (TechTarget, 2014). One goal of agile development is to build upon small-client-approved parts as the project progresses, as opposed to delivering one large application at the end of the project. One advantage to using agile methodology for the frequent shopper application is the ability to respond to changing requirements. KFF may decide to change the requirements of the project, which can easily be handled using the flexibility of the agile methodology. A second advantage is the face-to-face communication and continues input from customer representatives making sure that there is no guesswork (Buzzle, 2013). The result is exactly what the customer has required. The first disadvantage of the agile methodology is the possibility that the project can be taken off track. KFF is not one hundred percent clear on the final outcome that they want; therefore, the project has the potential to get off track because requirements are constantly changing. Another disadvantage is that it is difficult to assess the effort needed to complete this project at the beginning of the software development life cycle. Since KFF is not specific on the requirements for the project, we cannot plan how much time or the amount of resources we will need to complete the project. Regardless of the method that is used for the frequent shopper application, testing is a necessary component of the process. Testing is conducted differently depending on which software model is used. Since the waterfall method follows a sequential approach, the testing is done so also. The flexibility of the agile method also allows flexibility for the testing process. Using the waterfall method testing would begin during the implementation stage. The work would be divided into modules and the coding would begin after receiving the system design documents. The frequent shopper program would be developed into small programs called units. As an example, there would be a program that handles the input from the customer and another program that would track the employee’s reward points. Each unit is developed and then tested for functionality. Unit testing verifies if the units meet the specifications. The units are then integrated into a complete system during the integration phase and tested to see if all units coordinate between each other and the system functions as a whole per the specification (Onestoptesting, 2014). After testing of the frequent shopper program is successful, the software is delivered to the customer. If problems are found after deployment they are solved immediately. This is referred to be maintenance and sometimes that process is virtually never ending. Agile testing focuses on testing being an integral part of software development rather than a separate phase. (â€Å"Agile Testing†, n.d.) Testing from the beginning of the project and continually testing throughout the project lifecycle is the foundation in which agile testing is built. Agile testing is software testing based on the principles of agile software development. The combined team, including the testing team will take responsibility of analyzing the business requirements of the frequent shopper program. Together the team will define a sprint goal. The testing team will then begin work on the test plan that is validated by the entire team and KFF. As the development team starts the implementation, the test team will begin working on the test case design. When the code is ready to test, the test team will do a quick test on the development environment, in order to identify the early stage defects. Developers will fix the defects on a priority basis. This iteration will continue until the end of the code implementation. In addition after approval from KFF, automated test cases will be run on a daily basis. Because of the frequency of testing using the agile method, automated tests are needed. Smith Systems Consulting needs to choose the methodology that works for them and the client. Since each project is unique, there is not a one-size fit all methodology. Two alternative methods for completing this project were presented and Smith Systems Consulting can make a decision on which to choose. How to cite Frequent Shopper Program, Papers

Sunday, December 8, 2019

Everbright Commercial Enterprises for AXA - myassignmenthelp.com

Questions: 1.Explain to Ariana and Elsa if they are liable to pay for both the overdue accounts 2.Distinguish how the business of Fabulously You! would be run and managed if it were a limited liability partnership Answers: 1. The issue in this question is if Ariana and Elsa can be held liable to pay for the contracts created by Bella, particularly in view of the fact that it has been expressly stated in the partnership agreement that the object of the business will be to sell clothes that have been imported from Europe only and the sale of any other articles, other than clothes have been prohibited. Still, Bella had ordered a shipment of clothes from Korea and she had also ordered gemstones and jewelry worth $20,000. The law of partnership provides that each partner is considered to be liable jointly and severally along with all the other partners, regarding all the acts of the partnership business that have been done while such person remained a partner. Moreover, the law also provides that in this regard, the liability of all the partners is unlimited (Chiam Heng Hsien v Chiam Heng Chow, 2015). In view of the joint and several liability of the partners, the creditor of the partnership business may have civil causes of action. Therefore, it is available to the creditor of the partnership business to either sue the partners together or such creditor may also decide to sue the partners separately. On the other hand regarding the dealings between the partners themselves the partner who has paid for more than his share of the liability, as an option under the law to claim contribution from the other partners in accordance with the terms of the partnership agreement (Gabriel Peter Partners (suing as a firm) v Wee Chong Jin and othrs., 1997). The law also provides that when a partner who was acting within his apparent authority and has mis-applied the money or property of the business, either party can make the firm or any of its partners liable if the partner has misappropriated any money or property that was received either as a repayment of debt or as a loan on account of the firm. The law provides that every partner (and in case of his death, his estate) is liable for the debts and obligations of the firm that will incurred while such person was a partner of the firm (Chiam Heng Luan v Chiam Heng Hsien, 2007). In the same way, the partnership and all the partners can also be sued for any wrongful act that may be committed by a partner in the course of the usual business of the firm or being carried out with the authority of the other partners (Hely-Hutchinson v Brayhead Ltd., 1968). In the present case, Elsa was not taking an active part in the management of the partnership business owner although she was a partner of 20%. The business was merely being carried out by Ariana and Bella, but due to her pregnancy, Ariana also went on extended maternity. Under these circumstances, Bella was managing the shop alone. In order to boost the business of the partnership, Bella decided to order some clothes from a Korean supplier for $10,000. While doing so, she disregarded a clause present in the partnership agreed according to which, the partnership was going to sell clothes from Europe only. At the same time, in order to bolster revenue further, she also started purchasing semi-precious gemstones and jewelry. Therefore, she made an order to purchase gemstones and jewelry worth $30,000 from My Precious Jewels Pte Ltd. When the business failed to make these payments, the Korean supplier and My Precious Jewels Pte Ltd decided to sue the other partners, Ariana and Elsa. According to the law of partnership mentioned above, all the partners are treated by the law as being jointly and severally liable for the debts of the partnership business. Although there was a clause present in the partnership agreement, but that the parties were not aware regarding the presence of this clause, according to which the partnership business was going to sell the clothes imported from Europe only and it will not sell any other articles. Under these circumstances, it can be concluded that the Korean supplier and My Precious Jewels Pte Ltd. can sue the other two partners of the business, Ariana and Elsa for the recovery of their amount. 2. In this question, it needs to be described how the business of 'fabulously you' would have been run if it were a limited liability partnership. At the same time, it also needs to be discussed is the answer given about would have been different if 'Fabulously You' would have been registered as a limited liability partnership. The law provides that a limited liability partnership has to be considered as a separate legal entity. This entity has its own rights and liabilities that are separate from the rights and liabilities of the partners of the limited liability firm. This needs to be distinguished from a partnership where the law provides that all the partners have to be considered as being personally liable for the debts and obligations of the business. Similarly, the law also provides that each limited liability partnership should have at least two partners. In case the limited liability partnership is carrying on business with less than two partners for more than two years, the remaining partner may be held personally liable. In Singapore, a limited liability partnership (LLP) can be formed by two or more partners. This entity enjoys separate legal personality. As a result, this entity can sue or be sued in its own name. It also has the right to own property in its own name. The limited liability partnership provides the benefit of operational flexibility available in case of a partnership along with the benefits of limited liability that is available in case of the incorporation of a company. A limited liability partnership protects the partners from liability as a result of the willful misconduct or the gross negligence of one partner or a group of partners (Everbright Commercial Enterprises Pte Ltd v AXA Insurance Singapore Pte Ltd., 2000). In case of a limited liability partnership, all the partners are liable only after the extent of their contribution in the business. Therefore, in this case, they cannot be held personally liable. Regarding the debts and obligations of the limited in liability partn ership except in the cases where such debts and obligations have arisen due to their own negligence or fraudulence. The mutual rights and duties imposed on a limited liability partnership in Singapore and its partners are doing by the limited liability partnership agreement. Therefore, if the business of Fabulously You would have been run as a limited liability partnership, the other two partners of the business, Ariana and Elsa could not be held liable for making the payments to the Korean supplier or to My Precious Jewels Pte Ltd. for more than the amount that was enlisted by them in the partnership business of Fabulously You. In case the business of Fabulously You would have been run and managed as a limited liability partnership as compared to its present structure is a general partnership, the business would have been treated as a separate legal entity. Therefore the rights and obligations of the business would have been treated as the rights and obligations of the business itself and not of its partners. In the same way, if 'Fabulously You' would have been registered as a limited liability partnership, the debts and obligations of the business could not be enforced against its members. As a result, Ariana and Elsa could not be held liable to pay to the Korean supplier or to My Precious Jewels Pte Ltd for the clothes and jewelry that have been purchased by Bella. References Chiam Heng Hsien v Chiam Heng Chow [2015] 4 SLR 180 Chiam Heng Luan v Chiam Heng Hsien [2007] 4 SLR(R) 305 Gabriel Peter Partners (suing as a firm) v Wee Chong Jin and others [1997]3SLR(R)649 Hely-Hutchinson v Brayhead Ltd [1968] 1 QB 549 Everbright Commercial Enterprises Pte Ltd v AXA Insurance Singapore Pte Ltd [2000] 2 SLR(R) 287

Saturday, November 30, 2019

The Future of the Home Houses in 2030

Table of Contents Introduction Luxury Home 2030 Family Four Bedroom House Basic One Bedroom Flat Conclusion Reference List Introduction The achievements in the sphere of design and building show that within a short period of time, certain changes in house constructions may take place. One of the most spread thoughts is offered by Gerald Stryi-Hipp (2006): in 2030, the vast majority of homes will be heated by means of solar thermal only. Such choice will influence the use of energy and help society to save money reducing energy demands as well as improve the design of houses as there will be no need to use some electric tools.Advertising We will write a custom research paper sample on The Future of the Home: Houses in 2030 specifically for you for only $16.05 $11/page Learn More In this paper, the evaluation of three types of homes will be offered to define how materials and requirements for building as well as ethical aspects and technological use ma y be changed: a luxury home should be provided with a number of electronic gadgetry to help the owner save time and enjoy the design, a family four bedroom detached home aims at improving the life of a family, and a basic one bedroom flat with a number of significant attributes for living. Luxury Home 2030 Talking about the materials for a luxury home 2030, it is necessary to consider their nature. One of the most effective ways is to use special glass for luxury homes with the help of which the whole home is lightened and open for the sun, still, it is impossible to look through it. With the help of special digital technologies, it may be possible to change the colour of wallpapers in accordance with the owners’ mood. There is a special program implemented into the house that allows a person to choose from 1 to 5 colours. The following in-house technologies are possible for the chosen building: FM radio, digital TV that may be placed anywhere in the house, and furniture tran sformation. Due to the fact that the technologies are designed into the house before it is built, it is necessary to meet a number of requirements: solar thermal equipment that is located on the roof and provides the whole building with the necessary amount of solar energy, all walls are bearing and may be made of special pressured bricks and compressed earth blocks, and, finally, doors are made of strong wood that holds warm in the house. The chosen material and design meet the environmental green considerations. It is necessary to support the use of natural material in the building process, this is why the idea of unbroken glass as the main material for the luxury home is justified. Though a number of technologies and mechanisms are implemented into the house, all of them are inside the walls which are made of glass; so, they do not have some harmful effects on people living there. Family Four Bedroom House A family four bedroom house should be designed to provide a big family wit h all necessary services and quality: parents should be confident that their children are in safe, and children, in their turn, should have an access to the most important parts of the house. The material for this type home is wood or professional timber for the walls and roof, and metal rebar to create an appropriate floor.Advertising Looking for research paper on art and design? Let's see if we can help you! Get your first paper with 15% OFF Learn More As big families are not always able to spend much money on the technological aspects of their homes, it is possible to implement the most significant technologies: solar thermal at the roof (to support the green idea of building), heating technologies, and media improvements which are easy to use and hide in urgent cases. Kitchen technologies are integral in such type of building some members of the family spend much time in there. In relation to building design, a number of ethical issues should be considered to choos e building material properly and avoid harm for human health. Use of solar energy in heating is the most effective means that reduce the use of fossil fuels and other chemical substances. Basic One Bedroom Flat A first time buyer should get a number of benefits from a new basic one bedroom flat: building materials are usually concrete constructions which are supported by iron details. As a rule, one bedroom flat is a part of a huge construction, this is why it is necessary to define the bearing walls and implement as many technologies as possible in it. Solar energy is hardly available for such types of homes, still, it is possible to create one huge generator with the help of which heating and cooling of all flats in the building is controlled in one section. Environmental ethics should remind the designers about the importance to reduce the amount of waste and damage to the environment. Still, the following technologies should be implemented into the design as they influence the q uality of human life: security system due to which a person is sure of personal safe, media improvements with the help of which a person saves time and nerves, and entertaining aspects (bath equipment and kitchen accessibility). Conclusion In general, all above-mentioned buildings have one idea in common: people have to be protected from all outside damages and dangers: absence of chemical substances, attention to solar energy, and natural building materials are considered. In case the ethical perspective is pointed out while building and designing in 2030, there is a hope for all people to succeed in living and protect personal life to its full extent. Reference List Stryi-Hipp, G 2006, In 2030, many homes will be heated using only solar thermal, SBZ, pp. 40-44.Advertising We will write a custom research paper sample on The Future of the Home: Houses in 2030 specifically for you for only $16.05 $11/page Learn More This research paper on The Future of the Home: Houses in 2030 was written and submitted by user Aarav L. to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Tuesday, November 26, 2019

second draft essays

second draft essays Jurrasic Park Richard Graczyk JURASSIC PARK Crichton, Michael Publisher: Ballantine Books City Where Published: New York Date of latest copy: 1990 Edition: First Ballantine Books Edition: December 1991. 399 Pages, Hardcover I. A Brief Summary of the Plot. A billionaire has created a technique to clone dinosaurs. From the left behind DNA that his crack team of scientists and experts extract he is able to grow the dinosaurs in labs and lock them up on an island behind electrified fences. He has created a sort of theme park on the island which is located off the west coast of Costa Rica. The island is called Isla Nublar. He plans to have the entire planet come and visit his wondrous marvels. He asks a group of scientists from several different fields to come and view the park, but something terribly goes wrong when a worker on the island turns traitor and shuts down the power. II. A Description of the Most Important Aspects of the Contents. The main characters in the book are: John Hammond who is a billionaire developer who has used his resources to create the dinosaur filled island known as Jurassic Park. He is an old grandfather, and he dies in the book by a dinosaur known as a Procompsognathus. Dr. Alan Grant who is a renowned paleontologist who agrees to visit Jurassic Park only to find out it is the home of several Dinosaurs. Unlike the movie Dr. Grant loves kids in the book. He also had a of a beard. Dr. Ellie Sattler is a Paleobotinist and Alan Grant who is among the first people to tour Jurassic Park. Tim who is the 11 year old grandson of John Hammond. He is kind of geeky, into computers and loves Dinosaurs. His 7 year older sister is Alexis. She has a kind of tomboy attitude and loves base-ball Ian Malcom is the Mathematician that uses "Chaos Theory" to predict disastrous results. he only wears black and gray. He is presumably dead i...

Friday, November 22, 2019

Learn How to Pronounce German Words in English

Learn How to Pronounce German Words in English While the proper way to pronounce some German terms in English may be debatable, this isnt one of them: Porsche is a family name, and the family members pronounce their surname PORSH-uh. Can you remember when the French automaker Renault still sold cars in North America? (If youre old enough, you may recall Renaults Le Car.) In the early days, Americans pronounced the French name ray-NALT. Just about the time that most of us had learned to say ray-NOH correctly, Renault pulled out of the U.S. market. Given enough time, Americans usually can learn to pronounce most foreign words correctly- if you dont include ​maitre d or hors-doeuvres.   Example of Another Silent-E Another â€Å"silent-e† example is also a brand name: Deutsche Bank.   It could be a carryover from the now entrenched mispronunciation of Germanys former currency, the Deutsche Mark (DM). Even educated English-speakers may say â€Å"DOYTSH mark,† dropping the e. With the arrival of the euro and the demise of the DM, German company or media names with â€Å"Deutsche† in them have become the new mispronunciation target: Deutsche Telekom, Deutsche Bank, Deutsche Bahn, or Deutsche Welle. At least most people get the German â€Å"eu† (OY) sound right, but sometimes that gets mangled as well. Neanderthal or Neandertal Most informed people prefer the more German-like pronunciation nay-ander-TALL. Thats because Neanderthal is a German word and German does not have the th sound of English â€Å"the.† The Neandertal (the alternate English or German spelling) is a valley (Tal) named for a German by the name of Neumann (new man). The Greek form of his name is Neander. The fossilized bones of Neandertal man (homo neanderthalensis is the official Latin name) were found in the Neander Valley. Whether you spell it with a t or th, the better pronunciation is nay-ander-TALL without the th sound.   German Brand Names On the other hand, for many German brand names (Adidas, Braun, Bayer, etc.), the English or American pronunciation has become the accepted way to refer to the company or its products. In German, Braun is pronounced like the English word brown (same for Eva Braun, by the way), not BRAWN. But youll probably just cause confusion if you insist on the German way of saying Braun, Adidas (AH-dee-dass, emphasis on the first syllable) or Bayer (BYE-er). The same goes for Dr. Seuss, whose real name was Theodor Seuss Geisel (1904-1991). Geisel was born in Massachusetts to German immigrants, and he pronounced his German name SOYCE. But now everyone in the English-speaking world pronounces the authors name to rhyme with goose.   Frequently Mispronounced Terms German in Englishwith correct phonetic pronunciation Word/Name Pronunciation Adidas AH-dee-dass Bayer bye-er BraunEva Braun brown(not brawn) Dr. Seuss(Theodor Seuss Geisel) soyce GoetheGerman author, poet GER-ta (er as in fern)and all oe-words Hofbruhausin Munich HOFE-broy-house Loess/Lss (geology)fine-grained loam soil lerss (er as in fern) NeanderthalNeandertal nay-ander-tall Porsche PORSH-uh **Phonetic guides shown are approximate. English in Germanwith common German mispronunciation Wort/Name Aussprache airbag (Luftkissen) air-beck chatten (to chat) shetten corned beef kornett beff live (adj.) lyfe (live=life) Nike nyke (silent e) ornee-ka (German vowels)

Wednesday, November 20, 2019

Discuss the claim that, despite repeated reform, the Common Essay

Discuss the claim that, despite repeated reform, the Common Agricultural Policy (CAP) still retains its protectionist nature - Essay Example These regulations cover rural development, horizontal matters like financial support and controls, direct payments for farmers among others. Most critics view the Common Agricultural Policy as a form of protectionism meant to defend European producers from inexpensive products produced outside the European Union. This paper is going to discuss the claim that despite repeated reform, the Common Agricultural Policy retains its protectionist nature. Over the years, the European Union has been a model in regional integration and trade promotion trough out the world. This is evidenced by its move to cut many trade barriers through bilateral trade agreements, giving grants to poor countries, not forgetting that its creation has enhanced trade among the member states in a very significant way. Most importantly, it can be noted that the European Union is one of the trading blocs with lowest tariffs on imports from non-member states. Although this claim is true to some extent, the European Union protects Agriculture, which is one of its member states’ key industry sectors through the Common Agricultural Policy. The Common Agricultural Policy enacts trade barriers on agricultural produce from outside the European Union and at the same time subsidizing the domestic producers among its member states. Subsidies and artificially higher prices sometimes lead to overproduction, hence food surpluses in the European markets. The European Union in turn sells the excess supplies to the world market through subsidized exports, ensuring that domestic farmers enjoy higher income and job security. These subsidized export products are sold below the market prices, competing unfairly with products from developing economies. Some of the surpluses are stored to make the food mountains which are often destroyed when they cannot be sold. Consumers on the other hand are compelled to pay artificially higher prices for the food

Tuesday, November 19, 2019

Protein Extraction and Gel Electrophoresis Lab Report

Protein Extraction and Gel Electrophoresis - Lab Report Example The sodium dodecyl sulfate coats the proteins in proportion to their molecular weight and then confers the same negative electrical charge across all proteins in the sample. The rate of migration of a polypeptide in SDS-PAGE is inversely proportional to the logarithm of its molecular weight. This means that the larger the polypeptide, the slower it migrates in a gel. The molecular weight is determined by comparing the migration of protein spots to the migration of standards. Plots of log molecular weight versus the migration distance are reasonably linear. The proteins separated by SDS-PAGE are often recovered in a procedure that involves localizing the protein of interest on the gel following SDS-PAGE, eluting the protein from the gel, removing the sodium dodecyl sulfate from the eluted sample, and finally renaturing the protein for subsequent analysis. Proteins that are eluted from gels are used in varied downstream applications successfully, such as protein chemistry, determinatio n of amino acid composition, identification of polypeptides that correspond to specific enzyme activity, and other purposes.The analysis of protein concentrations is a significant assay in biochemistry research. The Bradford assay is one of the most widely used methods to determine concentrations of protein, relative to a standard. The technique is based on the formation of a complex between proteins in solution and the dye. This assay is commended for overall use, particularly for assessing concentrations of proteins for gel electrophoresis.... The proteins separated by SDS-PAGE are often recovered in a procedure that involves localizing the protein of interest on the gel following SDS-PAGE, eluting the protein from the gel, removing the sodium dodecyl sulfate from the eluted sample, and finally renaturing the protein for subsequent analysis. Proteins that are eluted from gels are used in varied downstream applications successfully, such as protein chemistry, determination of amino acid composition, identification of polypeptides that correspond to specific enzyme activity, and other purposes. The analysis of protein concentrations is a significant assay in biochemistry research. The Bradford assay is one of the most widely used method to determine concentrations of protein, relative to a standard. The technique is based on the formation of a complex between proteins in solution and the dye, Brilliant Blue G. This assay is commended for overall use, particularly for assessing concentrations of proteins for gel electrophores is. It is based on observations that absorbance maximum for acidic mixtures of Coomassie Brilliant Blue G-250 that do shift from 465 nm up to 595 nm at a time when protein binding occurs. The assay is effective because of the extermination coefficient of the albumin-dye complex solution is usually constant over a range of 10-fold concentration (Westermeier, Naven & Ho?pker, 2008). The dye reacts mainly with arginine residues but less with histidine, lysine, tryptophan, tyrosine, and phenylalanine residues. Seemingly, this examination is not all that perfect for acidic or basic proteins. However, it is somewhat sensitive to the bovine serum albumin, even more than most proteins, by a factor of two. Gamma globulin (IgG) is the protein standard of preference. The objective of this

Saturday, November 16, 2019

Family System Theory Essay Example for Free

Family System Theory Essay In my attempt to outline a family seeking therapy for domestic violence using the Family Systems Theory, I will first give a detailed account of the family history, and then embark on the problem before tackling the intervention strategy. Family History John married Jane 20 years ago.   At the time of their marriage, John had a well paying job which could support his nuclear family as well as his parents.   Johns parents were peasant farmers who actually had sold everything they had in order to pay Johns school fees.    Johns parents had placed a lot of hope in him before he contracted this marriage. This fact led them to discourage John from marrying Jane since they considered that John having spent the family resources in his education, he had every reason first to pay school fees for his young brothers.   To avoid clashing with his parents, John promised to handle both responsibilities (that is, caring for the younger siblings and his wife).   After lengthy deliberations the parents submitted to his observations and allowed him to go forward and marry Jane. On the other hand, Jane at the time of marriage was employed as a sales girl and earned amount that could see her through most of her needs.   Jane appeared to be a self styled lady depicting a lot of wealth.   Even though Janes parents were notoriously religious, Jane had an out of wedlock child which she was caring at her parents. This issue was however unknown to John. Jane did not bother or she ignored to disclose to John about this issue.   John only happened to know about the kid a few weeks to their wedding day.   This did not detract John from marrying her fiancà ©e. Jane was the last born in a family of six children, 3 girls and 3 boys.   Her parents were wealthy and of middle social standing.   This family not only was it capable of meeting basic needs but also some luxuries.   Her elder brothers were all married and comfortably settled down.   The two elder girls were also married to wealthy husbands who owned some assortments of luxurious properties including several vehicles.   Unlike Johns family, Janes family was in actual fact composed of well to do family members. It is important to note that Janes educational background was not pleasing as she had dropped out of school when she contracted her first pregnancy.   John however, had knowledge of her lovers, educational background and seemed to be contended with the situation.   At first, when Jane highlighted to her parents about her future prospects, they at first disapproved the marriage on the grounds that John could afterwards ditch her due to her first child or due to her educational standards.   Jane succeeded to bargain for blessing of the marriage through cheating her parents that John was aware of everything, thus there was no cause of worry. The Problem As noted earlier, few days after John married Jane, there was a misunderstanding over the first issue as John demanded an apology from Jane for failing to disclose fully her status.   This time the marriage was saved by the intervention of Johns parents who pleaded with him to shelve the matter and love his wife as before. Joy returned to these couples and within a period of 10 years, they had 3 more children inside the wedlock.   John managed to convince Jane to leave her job so as to concentrate with family matters, which included taking care of the children among others. This move however, was viewed by Johns in-laws negatively as they considered Johns salary to be insufficient.   They also had negative thoughts about the future status of their daughters marriage, as they had conviction that John would one day ditch Jane.   They rebuked Jane for being seduced to terminate her employment. During the 15 years into marriage, John was suspended from his employment under very queer circumstances.   What happened is that John, while supposed to be on duty, had that day requested a fellow workmate to play his part, while he attended to some family issues. Unfortunately, the same day, there occurred some robbery at his place of work and more particularly involving his department.   This called for his suspension pending investigation that was followed by his dismissal without terminal benefits. Upon dismissal John and his family moved to there rural home. Coping with life was not easy as the family had to readjust and face some of the realities of life. The family was in total economic disrepair and john for the sake of saving the situation sold most of his rag-tag assets. However the going was not smooth as these did not last the family for a ling time. As a way of escaping realities of life, John started to drink. This only served the purpose of increasing his problems. Upon being confronted by her wife he resorted to abusive language. The problem facing the family now is that as a result of John’s change of behavior Jane’s parents are blaming her for failing to listen to their instructions in the first place. Even though they have secured Jane something to see the family through basic needs, they are threatening to withhold the same if she keeps on sticking to this doomed marriage. On the other hand John’s children seem to be suffering from emotional distress due to the misunderstanding pitying the parents. The out of wed-lock daughter is considering that their father is battering her mother due to her presence in the family. John seems to be sinking deep and deeper in drug and substance abuse. He abuses his children through neglect as well as physically associating them. John’s parents seem to suggest that John made a mistake in marrying Jane for reasons which are not clear. The family is about to break-down as john is engaged in all manner of domestic violence. Sometime when drunk he raises the subject of the first daughter, a topic that Jane considers to have been dealt with in the past. He also sees Jane’s parents to be the source of all his problems as he associates them with wealthy bureaucrats who are out to play down his marriage. There is total communication breakdown in John’s family as well as between the extended family (in-laws). The family with the aid of a Good Samaritan is now seeking therapy. Remember Jane is cursing herself for having disrespectful to her parent’s advice. The same thing is also happening to John. This culminates into the children loosing hope. Therapy The therapy required here should encompass all the members of the nuclear as well as the extended family. First it is important to evaluate the family through scheduling interviews that involves with some members of this immediate family. This interview should include children as well as two significant members of the extended family. There is a need for the therapist to be a man and woman as to treat gender related issues on top of serving as role models for the family. The therapy being based on the family systems theory the family should be regarded wholly as being the unit of treatment. Therefore emphasis should be placed on communication processes. John’s family should be analyzed first. Therapist’s comments and remarks should be structured in a manner likely to help family members become more conscious of patterns or structures that had been previously ignored. Sessions should be structured in a way that members of the extended family can, eat together, so as to afford the most required ingredient of family to succeed-communication. By the end of the therapy members of this family including the IP (Identified Patient) should be seen to differentiate. Reference Nichols, M.P. Schwartz, R.C. (2006). Recent Developments in Family Therapy: Integrative Models; in Family therapy: concepts and methods. 7th Ed. Boston: Pearson/Allyn Bacon.

Thursday, November 14, 2019

Rap as a language Essay examples -- essays research papers

  Ã‚  Ã‚  Ã‚  Ã‚  Since its start in the music industry around nineteen eighty-eight rap music has always been under a lot of scrutiny for its lyrics and messages that it portrays. Rap music has a long history starting back to the days of slavery and has come a long way since then bridging gaps between all genres of music including jazz, blues, and basic drum beats. When hip hop first came about its message was simple. It was groups of black men who described the life they were living in the ghettos all over the world. They felt helpless and viewed the government in a very strong negative way based on the lack of help African American’s were given in the contexts of housing, education, and living. As rap music developed and more artists started bringing their own styles to the hip hop community more messages were being brought. Hip hop as a culture was formed on the political views of many black gang bangers who society cast aside and never thought would even be able to have political thoughts. In the mid nineties rap changed in a way that surprised many by having female artists come onto the scene. They were usually portrayed in a degrading manner by male artists in their lyrics and videos, but now women came forward and described themselves as sexual beings and how they have power over men based on their sexuality. Many critics have taken these stances that rap artists take and speculated over whether or not they convey a positive or negative message. Many view that the lyrics and videos provide children with the wrong idea and are the reason for sex at younger ages, and STD’s being at an all time high. Rap is not responsible for the actions of young adults and music has always been a scapegoat for parents since the days of Elvis, and KISS. Rap is like all other genres of music in the sense that it is a statement. During times of war artists criticized presidential actions and sang about peace. Rap is a declaration of life for black men and qu estions the politics involved in their lifestyles and for women it is a way to express themselves as powerful independent beings because of their sexuality.   Ã‚  Ã‚  Ã‚  Ã‚  Stereotypes are often placed into the minds of many people in the general public based on fixed images set in the minds of many MTV viewers. This has always been the case with generational music culture to fight for mor... ...in the ghettos of the world. He claims that rap is a political stance and a language that is powerful in its ability to create movement and progress in the minds of its audience. This helps my argument because this is exactly what I want to argue. It gives crucial examples of how and why rap music can stand alone as its own well educated language. Rose, Tricia. â€Å"Fear of a Black Planet†: Rap Music and Black Cultural Politics in the 1990’s. The Journal of Negro Education vol. 60 (1991) 276-290. Rose argues that hip hop music in the 1990’s when it really began to make a name for itself came out with bang that seemed to slap many unsuspecting people in the face with its crude lyrics and â€Å"I don’t care† mentality. She gives quotes and respect to many groups of that time such as NWA and Public Enemy who gave face to the up rise of gangster rap and gave a window into the lives that black men and women where actually living. This helps my argument because I mainly was going to quote lyrics from the 1990’s because that was when rap was most political. I am however going to quote some more recent rappers such as Eminem to show how that decade has still rolled over to today’s generation.

Monday, November 11, 2019

Novel Nicholas Nickleby Essay

Mr Squeers is one of Charles Dickens’ very vivid characters and one that plays an important role in the novel Nicholas Nickleby. He is owner and headmaster of Dotheboys Hall which is set in Greta Bridge in Yorkshire. Dotheboys Hall is a boarding school for disabled and illegitimate children. It is an all-boys school and Mr Squeers runs the school with extreme cruelty together with his wife, who is equally cruel. The children are sent there because they are disabled in some way and their families did not want them. Mr Squeers has very cunning ways and his only aims are to benefit himself. His main aim is to make money and he does this very well by being sneaky and taking short-cuts in the keeping of his school. He tries to put as little money as possible to Dotheboys Hall whilst getting as much money out as possible. Another of his objectives is to have the instant obedience that he desires. He wants a school where he has ultimate power over the boys so that when he asks something of them they do it immediately – with no question. He tries to obtain this instant obedience in school by regularly beating the boys with a cane. Mr Squeers sees his school more as a business than a school-learning environment. â€Å"This is our shop, Nickleby†. This quote shows that he is treating the school as a business because his primary objective is to make money. He does not really care about the boys’ education, just as long as he turns over a nice profit. As Mr Squeers is owner of Dotheboys Hall he decides how to teach the boys or not, as the case may be. Mr and Mrs Squeers deeply dislike all of the boys in their school, except their own children. In fact they perceive the boys as â€Å"their natural enemies†. Clearly, if they see the boys like this then they are not fit to run a school but as it is their own school, they can do as they like. Mr and Mrs Squeers both hate the boys. â€Å"The only difference between them is that Mrs Squeers wages war against the boys openly whilst Mr Squeers tries to cover his rascality†. I think Mr Squeers tries to cover his rascality because he knows that he is not treating the boys very well and should not be doing this. However, don’t be fooled! Mr Squeers hates the boys as much as his wife but Mrs Squeers doesn’t really look for an excuse to beat them – she just enjoys doing it. All of the boys at Dotheboys Hall are terrified of Mr and Mrs Squeers and live in fear of the dreaded cane which they both use to mercilessly beat them. At the Hall, the boys don’t get much freedom and think what they are told to think. They dare not argue or answer back to Mr Squeers as they are kept too weak and undernourished. It is clear that the boys are scared of him because of the amount of times and the violent manner in which Mr Squeers uses the cane.

Saturday, November 9, 2019

National Culture Essay

In other words, although the concept of â€Å"nation† unfairly characterizes colonized subjects as istorically unified in their primitiveness or exoticness, the term’s promise of solidarity and unity often proves helpful nonetheless In their attempts at political amelioration. Fanon encourages a materialist conceptualization of the nation that is based not so much on collective cultural traditions or ancestor-worship as political agency and the collective attempt to dismantle the economic foundations of colonial rule. Colonialism, as Fanon argues, not only physically disarms the colonized subject but robs her ofa â€Å"pre-colonial† cultural heritage. And yet, if colonialism in this sense alvanizes the native intellectual to â€Å"renew contact once more with the oldest and most pre-colonial spring of life of their people,† Fanon is careful to point out that these attempts at recovering national continuity throughout history are often contrived and ultimately self-defeating. l am ready to concede,† he admits, â€Å"that on the plane of factual being the past existence of an Aztec civilization does not change anything very much in the diet of the Mexican peasant of today. † In the passage below, Fanon explains that â€Å"national identity only carries meaning insofar as it eflects the combined revoluuonary efforts of an oppressed people aiming at collective liberation: A national culture is not a folklore, not an abstract populism that believes It can discover the people ’s true nature. It Is not made up of the Inert dregs of gratuitous actions, that is to say actions which are less and less attached to the ever-present reality of the people. A national culture is the whole body of efforts made by a people in the sphere of thought to describe, Justify, and praise the action through which that people has created Itself and keeps Itself In existence. Muhammad Slbtaln Haider 11-12-2013 National Culture By sibtainJaf because it re-inscribes an essentialist, totalizing, fetishized, often middle-class solidarity and unity often proves helpful nonetheless in their attempts at political but robs her of a â€Å"pre-colonial† cultural heritage. And yet, if colonialism in this sense below, Fanon explains that â€Å"national identity† only carries meaning insofar as it reflects the combined revolutionary efforts of an oppressed people aiming at believes it can discover the people’s true nature. It is not made up of the inert dregs through which that people has created itself and keeps itself in existence. Muhammad Sibtain Haider

Thursday, November 7, 2019

8 Simple Rules for Russian Verb Conjugation

8 Simple Rules for Russian Verb Conjugation Russian verbs change according to their tense, person, and number. This guide to Russian verb conjugation provides basic rules for conjugating regular verbs in the present tense. The Russian present tense is simpler than the English present tense, as there is only one present tense verb form. To illustrate this point, consider the sentence Ã'  Ã'‡Ð ¸Ã'‚Ð °Ã'Ž. This statement can mean I read, I have been reading, or I am reading. Thanks to this simplified present tense, basic verb conjugation in Russian is easier than you might expect. Follow these eight steps to begin conjugating Russian verbs. Rule 1: Russian Verb Forms Russian verbs have six forms in the present tense: 1st person, 2nd person, and 3rd person, all of which can be singular or plural. The verb ending tells us the point of view (1st, 2nd, or 3rd) and the number (singular/plural) of the verb. Rule 2: Verb Conjugation Groups There are two groups of verb conjugation in Russian: first conjugation and second conjugation. First conjugation verbs have the endings -Ã'Æ' (-Ã'Ž),  -Ð µÃ'ˆÃ'Å' (-Ã'‘Ã'ˆÃ'Å'),  -Ð µÃ'‚ (-Ã'‘Ã'‚),  -Ð µÃ ¼ (-Ã'‘Ð ¼),  -Ð µÃ'‚Ð µ (-Ã'‘Ã'‚Ð µ), and -Ã'Æ'Ã'‚ (-Ã'ŽÃ'‚). Second conjugation verbs have the endings -Ã'Æ' (-Ã'Ž),  -Ð ¸Ã'ˆÃ'Å',  -Ð ¸Ã'‚,  -Ð ¸Ã ¼,  -Ð ¸Ã'‚Ð µ,  -Ð °Ã'‚ (-Ã' Ã'‚).   Rule 3: How to Check a Conjugation Group There are two ways to determine a verbs conjugation group. First, look at the personal ending if it is under stress: Ð ¿Ã µÃ'‚Ã'Å' – Ð ¿Ã ¾Ã'‘Ã'ˆÃ'Å', Ð ¿Ã ¾Ã'‘Ã'‚, Ð ¿Ã ¾Ã'ŽÃ'‚ (first conjugation)Ð ³Ã'€Ð µÃ ¼Ã µÃ'‚Ã'Å' – Ð ³Ã'€Ð µÃ ¼Ã ¸Ã'ˆÃ'Å', Ð ³Ã'€Ð µÃ ¼Ã ¸Ã'‚ (second conjugation) Second, if the personal ending is not stressed, look at the suffix before the ending -Ã'‚Ã'Å' in the infinitive form of the verb and follow these steps. Put the verb in its infinitive, e.g. Ð ³Ã'Æ'Ð »Ã' Ã µÃ'‚ - Ð ³Ã'Æ'Ð »Ã' Ã'‚Ã'Å'Check which vowel comes before the ending -Ã'‚Ã'Å'. For example: in Ð ³Ã'Æ'Ð »Ã' Ã'‚Ã'Å', it is Ã' .Use these rules to determine whether the verb is first or second conjugation. Rule 4: Endings in Second Conjugation Verbs Second conjugation verbs are: All verbs ending in -Ð ¸Ã'‚Ã'Å' in their infinitive form (exceptions: Ð ±Ã'€Ð ¸Ã'‚Ã'Å', Ã' Ã'‚Ð µÃ »Ã ¸Ã'‚Ã'Å')7 verbs ending with -Ð µÃ'‚Ã'Å': Ã' Ã ¼Ã ¾Ã'‚Ã'€Ð µÃ'‚Ã'Å', Ð ²Ã ¸Ã ´Ã µÃ'‚Ã'Å', Ð ½Ã µÃ ½Ã °Ã ²Ã ¸Ã ´Ã µÃ'‚Ã'Å', Ð ·Ã °Ã ²Ã ¸Ã' Ã µÃ'‚Ã'Å', Ã'‚Ð µÃ'€Ð ¿Ã µÃ'‚Ã'Å', Ð ¾Ã ±Ã ¸Ã ´Ã µÃ'‚Ã'Å', Ð ²Ã µÃ'€Ã'‚Ð µÃ'‚Ã'Å'4 verbs ending with -Ð °Ã'‚Ã'Å': Ã' Ã »Ã'‹Ã'ˆÐ °Ã'‚Ã'Å', Ð ´Ã'‹Ã'ˆÐ °Ã'‚Ã'Å', Ð ³Ã ½Ã °Ã'‚Ã'Å', Ð ´Ã µÃ'€Ð ¶Ã °Ã'‚Ã'Å'All derivatives of these verbs, e.g. Ð ¿Ã µÃ'€Ð µÃ ³Ã ½Ã °Ã'‚Ã'Å', Ð ¿Ã'€Ð ¾Ã' Ã ¼Ã ¾Ã'‚Ã'€Ð µÃ'‚Ã'Å' Rule 5: Endings in First Conjugation Verbs First Conjugation verbs are those that in their infinitive form end in -Ð µÃ'‚Ã'Å', -Ð °Ã'‚Ã'Å', -Ã' Ã'‚Ã'Å', -Ð ¾Ã'‚Ã'Å', -Ã'Æ'Ã'‚Ã'Å', -Ã'‹Ã'‚Ã'Å'. Rule 6: How to Remember The Correct Conjugation Group Heres a helpful poem to remember which verbs are in the second conjugation group. КÐ ¾ Ð ²Ã'‚Ð ¾Ã'€Ð ¾Ã ¼Ã'Æ' Ð ¶Ã µ Ã' Ã ¿Ã'€Ã' Ã ¶Ã µÃ ½Ã'Å'Ã'ŽÐžÃ'‚Ð ½Ã µÃ' Ã µÃ ¼ Ð ¼Ã'‹ Ð ±Ã µÃ · Ã' Ã ¾Ã ¼Ã ½Ã µÃ ½Ã'Å'Ã' Ãâ€™Ã' Ã µ Ð ³Ã »Ã °Ã ³Ã ¾Ã »Ã'‹, Ã'‡Ã'‚Ð ¾ Ð ½Ã ° –Ð ¸Ã'‚Ã'Å',ИÃ' Ã ºÃ »Ã'ŽÃ'‡Ð °Ã'  Ð ±Ã'€Ð ¸Ã'‚Ã'Å', Ã' Ã'‚Ð µÃ »Ã ¸Ã'‚Ã'Å',Ð  Ð µÃ'‰Ð µ: Ã' Ã ¼Ã ¾Ã'‚Ã'€Ð µÃ'‚Ã'Å', Ð ¾Ã ±Ã ¸Ã ´Ã µÃ'‚Ã'Å', Ã' Ã »Ã'‹Ã'ˆÐ °Ã'‚Ã'Å', Ð ²Ã ¸Ã ´Ã µÃ'‚Ã'Å', Ð ½Ã µÃ ½Ã °Ã ²Ã ¸Ã ´Ã µÃ'‚Ã'Å',Ð ³Ã ½Ã °Ã'‚Ã'Å', Ð ´Ã'‹Ã'ˆÐ °Ã'‚Ã'Å', Ð ´Ã µÃ'€Ð ¶Ã °Ã'‚Ã'Å', Ã'‚Ð µÃ'€Ð ¿Ã µÃ'‚Ã'Å',Ð ¸ Ð ·Ã °Ã ²Ã ¸Ã' Ã µÃ'‚Ã'Å', Ð ¸ Ð ²Ã µÃ'€Ã'‚Ð µÃ'‚Ã'Å'. Rule 7: Finding The Stem To find the stem of a verb, take away the last letter from the first person singular form of the verb (Ã' ). For example, Ã'  Ð ³Ã'Æ'Ð »Ã' Ã'Ž becomes Ð ³Ã'Æ'Ð »Ã' . Next, take off the last three letters the ending from the second person singular form of the verb (Ã'‚Ã'‹). For example, Ã'‚Ã'‹ Ð ³Ã'Æ'Ð »Ã' Ã µÃ'ˆÃ'Å' becomes Ð ³Ã'Æ'Ð »Ã' . Finally, compare the two results. If they are the same, either result is the stem. If they are not the same, then the second result is the stem. Rule 8: Attaching The Ending Take the stem of your verb (Ð ³Ã'Æ'Ð »Ã' ) and find the correct ending based on the verbs conjugation group. If it is a first conjugation verb, use the endings -Ã'Æ' (-Ã'Ž),  -Ð µÃ'ˆÃ'Å' (-Ã'‘Ã'ˆÃ'Å'),  -Ð µÃ'‚ (-Ã'‘Ã'‚),  -Ð µÃ ¼ (-Ã'‘Ð ¼),  -Ð µÃ'‚Ð µ (-Ã'‘Ã'‚Ð µ), and -Ã'Æ'Ã'‚ (-Ã'ŽÃ'‚). If it is a second conjugation verb, use the endings -Ã'Æ' (-Ã'Ž),  -Ð ¸Ã'ˆÃ'Å',  -Ð ¸Ã'‚,  -Ð ¸Ã ¼,  -Ð ¸Ã'‚Ð µ,  -Ð °Ã'‚ (-Ã' Ã'‚). Exceptions Some verbs are conjugated with endings from both the first and the second conjugation forms. For example: Ã'  Ã'…Ð ¾Ã'‡Ã'Æ' (ya khaCHOO) - I wantÃ'‚Ã'‹ Ã'…Ð ¾Ã'‡Ð µÃ'ˆÃ'Å' (ty KHOchysh) - you wantÐ ¾Ã ½ / Ð ¾Ã ½Ã ° Ã'…Ð ¾Ã'‡Ð µÃ'‚ (on / aNA KHOchyt) - he / she wantsÐ ¼Ã'‹ Ã'…Ð ¾Ã'‚Ð ¸Ã ¼ (my khaTEEM) - we wantÐ ²Ã'‹ Ã'…Ð ¾Ã'‚Ð ¸Ã'‚Ð µ (vy khaTEEty) - you wantÐ ¾Ã ½Ã ¸ Ã'…Ð ¾Ã'‚Ã' Ã'‚ (aNEE khaTYAT) - they want Ã'  Ð ±Ã µÃ ³Ã'Æ' (ya byeGOO) - I am running / I runÃ'‚Ã'‹ Ð ±Ã µÃ ¶Ã ¸Ã'ˆÃ'Å' (ty byeZHYSH) - you (singular / familiar) are running / you runÐ ¾Ã ½ / Ð ¾Ã ½Ã ° Ð ±Ã µÃ ¶Ã ¸Ã'‚ (on / aNA byZHYT) - he / she is running / he / she runsÐ ¼Ã'‹ Ð ±Ã µÃ ¶Ã ¸Ã ¼ (my byZHYM) - we are running / we runÐ ²Ã'‹ Ð ±Ã µÃ ¶Ã ¸Ã'‚Ð µ (vy byZHYty) - you (plural) are running / you runÐ ¾Ã ½Ã ¸ Ð ±Ã µÃ ³Ã'Æ'Ã'‚ (aNEE byGOOT) - they are running / they run First Conjugation Example Ð ³Ã'Æ'Ð »Ã' Ã'‚Ã'Å' (gooLYAT) - to walk, to strollÐ ³Ã'Æ'Ð »Ã'  - the verbs stem Ã'  Ð ³Ã'Æ'Ð »Ã' Ã'Ž (ya gooLYAyu) - I am walking / I walkÃ'‚Ã'‹ Ð ³Ã'Æ'Ð »Ã' Ã µÃ'ˆÃ'Å' (ty gooLYAysh) - you (singular / familiar) are walking / you walkÐ ¾Ã ½/Ð ¾Ã ½Ã ° Ð ³Ã'Æ'Ð »Ã' Ã µÃ'‚ (on/aNA gooLYAyt) - he / she is walking / he/ she walksÐ ¼Ã'‹ Ð ³Ã'Æ'Ð »Ã' Ã µÃ ¼ (my gooLYAyim) - we are walking / we walkÐ ²Ã'‹ Ð ³Ã'Æ'Ð »Ã' Ã µÃ'‚Ð µ (vy gooLYAytye) - you (plural) are walking / you walkÐ ¾Ã ½Ã ¸ Ð ³Ã'Æ'Ð »Ã' Ã'ŽÃ'‚ (aNEE gooLYAyut) - they are walking / they walk Second Conjugation Examples Ð ´Ã'‹Ã'ˆÐ °Ã'‚Ã'Å' (dySHAT) - to breatheÐ ´Ã'‹Ã'ˆ - the verbs stem Ã'  Ð ´Ã'‹Ã'ˆÃ'Æ' (ya dySHOO) - I am breathing / I breatheÃ'‚Ã'‹ Ð ´Ã'‹Ã'ˆÐ ¸Ã'ˆÃ'Å' (ty DYshysh) - you (singular / familiar) are breathing / you breatheÐ ¾Ã ½/Ð ¾Ã ½Ã ° Ð ´Ã'‹Ã'ˆÐ ¸Ã'‚ (on / aNA DYshyt) - he / she is breathing / he / she breathesÐ ¼Ã'‹ Ð ´Ã'‹Ã'ˆÐ ¸Ã ¼ (my DYshym) - we are breathing / we breatheÐ ²Ã'‹ Ð ´Ã'‹Ã'ˆÐ ¸Ã'‚Ð µ (vy DYshytye) - you (plural) are breathing / you breatheÐ ¾Ã ½Ã ¸ Ð ´Ã'‹Ã'ˆÐ °Ã'‚ (aNEE DYshut) - they are breathing / they breathe Ð ²Ã ¸Ã ´Ã µÃ'‚Ã'Å' (VEEdyt) - to seeÐ ²Ã ¸Ã ´ - the verbs stem Ã'  Ð ²Ã ¸Ã ¶Ã'Æ' (ya VEEzhoo) - I am seeing / I see*Ã'‚Ã'‹ Ð ²Ã ¸Ã ´Ã ¸Ã'ˆÃ'Å' - you (singular / familiar) are seeing/ you seeÐ ¾Ã ½ / Ð ¾Ã ½Ã ° Ð ²Ã ¸Ã ´Ã ¸Ã'‚ - he / she is seeing / he / she seesÐ ¼Ã'‹ Ð ²Ã ¸Ã ´Ã ¸Ã ¼ - we are seeing / we seeÐ ²Ã'‹ Ð ²Ã ¸Ã ´Ã ¸Ã'‚Ð µ - you (plural) are seeing / you seeÐ ¾Ã ½Ã ¸ Ð ²Ã ¸Ã ´Ã' Ã'‚ - they are seeing / they see (*Please note that in some verbs, consonants positioned before the personal endings can change. Here, Ð ´ changes to Ð ¶ in first person singular.)

Monday, November 4, 2019

Brand audit of cadbury dairy milk

The journey of Cadbury started way back in the year 1905 from Bourneville, UK. But it came to Indian market in 1948. From the time it was introduced in India, Dairy Milk has been the market leader in the confectionery segment. It has average daily sales of 1 Million bars. The reason that our group chose Cadbury Dairy Milk for the Brand Audit is that it provides us with ample scope to study the various aspects of Branding like Communication Strategies, Innovative Ad Campaigns, and Emotional Connect with Consumers, Brand Repositioning, and Rebranding etc†¦ We will study the evolution of Cadbury Dairy Milk by focusing on following Aspects: In 1824, John Cadbury opened a shop in Birmingham. This one-man business, trading mainly in Tea Coffee was to be the foundation of Cadbury Limited. For over 100 years Cadbury was a family business. In 1943 non family directors were appointed. In 1847, the enterprise had prospered to a large factory in Bridge Street, Birmingham. John Cadbury took his brother Benjamin into partnership and the family business became Cadbury Brothers Birmingham. The business moved to Bourneville after outgrowing the Bridge Street Factory. The Workforce had risen up to 200 after 32 years at Bridge Street. After the death of two brothers in 1899, the company was privatized. It entered the era of scientific management; it introduced new ideas for their department like: On 2nd February, Kraft Foods took over 71% shares of Cadbury. They acquired it totally. But still Cadbury was on top in the market. This acquisition did not changed people’s mind and their craze for Cadbury Dairy Milk. OPERATIONS Cadbury’s operations are carried out in many countries. Few of them are: BRAND ELEMENTS Dairy Milk has been meticulously built around the world by Cadbury. It has been able to sustain a strong position in the market. There are many branding elements which have resulted into consistent result of its success. Few core Branding Elements are as given below: Not only the above three, But there are many more elements due to which the consistent Branding of Dairy Milk is so very popular. Its different Advertisements, its punch lines etc†¦ It has always kept a strong association with Milk, with slogans such as â€Å"a glass and half of full cream milk in every half pound. And also advertisement which featured a glass of milk pouring out and forming the Dairy Milk bar. Also the ad campaigns are also the important element of Dairy Milk. It made chocolate an eating habit among the consumers, especially the adults. Long back it was a belief that chocolate is only for kids. But Dairy Milk changed this belief. Also they changed the trend of Sweets (Mithai) during the occasions like Diwali, New Year etc†¦ Dairy Milk brought a new trend that whether any occasion, Dairy Milk is best for all. It also gave some famous dialogues from the ads which people remember always. They were also the core brand elements of Dairy Milk. Let us see them below: All these above dialogues were form the very famous and popular ad’s of Dairy Milk. By this ad they wanted to covey to the people that for eating Dairy Milk they do not have to wait for any occasion. They can just have it. Whether they are happy or Sad, But Dairy Milk can be taken in any of the mood. BRAND PORTFOLIO Worldwide In June 1905, Cadbury launched its first Dairy Milk bar, with a higher proportion of milk and it became the best selling product of the company by 1913. Fruit and Nut was introduced in 1928. In 2003, Cadbury made Dairy Milk into a family brand by taking the brands like Caramel, Whole Nut, and Wispa and marketed them as the sub-brands of Dairy Milk. By 2006, there were 15 Dairy Milk sub-brands produced in UK including Shortcake Biscuit, Wafer, Orange Chips, Mint Chips, Crispies and Cream Egg. In following two years these brands were discontinued as they were not successful. Indian Market The Dairy Milk Brand alone accounts for approximately 33% of total Cadbury’s sales. It has made Cadbury the number one confectionery brand in the market. Currently in India, Dairy Milk has following sub-brands under its name. They are; BRAND POSITIONING The Brand Positioning of Cadbury Dairy Milk in mid 90’s was that chocolate is not only for kids but also for adults. And to prove this they immediately released the very popular† Real Taste of Life† campaign , shifting the focus from â€Å"just for kids† to â€Å" kid in all of us†. Let us see the Brand Positioning of Dairy Milk on segmentation bases on two main bases. And they are: Demographic Dairy Milk silk is little higher in cost compared to ordinary Dairy Milk, Fruit and Nut and Crackle. But still people love to have Dairy Milk. Silk is the premium Brand of Dairy Milk Behavioral As we know that Dairy Milk is the only Brand who is the only one to promote chocolate as an important part of Festivals as well as it changed the mind sets of the people that chocolate is not only for kids but for all. The strategy to target adults was taken further with the help of a brand new positioning â€Å"Kuch Meetha Ho Jaye†. For Indians occasions and festivals have utmost importance and Dairy Milk rigorously focused on this point and set a new trend of having Dairy Milk in place of â€Å"Mithai† during the occasions. COMMUNICATION STRATEGY Up to 2002, Cadbury was the one having 70 % market shares in chocolate industry. Out of which 30% was the Dairy Milk alone. This is because of constant re-invention of the brand bombarding communication towards the consumers consistently to maintain the top position in mind recall in confectionery segment. Dairy Milk was awarded as No. 1 most trusted brand in Mumbai 2005 for the edition of Brand Equity’s most trusted Brand Survey. Dairy Milk targeted all the aspects as possible to get into the heart of all the people, of all age groups. For this they communicated with people through different Ad’s Campaigns. Let us see few of them below: Shubh Aarambh was one of successful campaigns of Dairy Milk. This means Auspicious Beginning. With this campaign they said that for whatever you start, start it with Dairy Milk and it will be successful. For this they chose the best to advertise: Amitabh Bacchhan. Tools for Communication Dairy Milk used different media options to communicate different campaigns and promote Dairy milk. They are: TV Advertisements is the most popular method for Dairy Milk to show their new campaigns to people so that they can more and more relate it with their personal lives. They also have ground promotions in different malls. They arrange some contests also to promote their brand. DISTRIBUTION STRATEGY As we know that Dairy Milk holds 30% value share of chocolate market. The demand of chocolate is increasing day by day. And Dairy Milk is no. 1 in that race. Indian market specifically where the penetration of chocolates is increasing, brings a need for efficiency in logistics and distribution. There is stiff competition in the confectionery market due to large exposure of foreign currency rate risk, mainly on account of import of cocoa beans, cocoa butter. Cadbury Dairy Milk is easily available anywhere in the market. Cadbury’s success of proper distribution is their efficiency. PRICING STRATEGY Dairy Milk is positioned towards age group of 4-50, and thus the price is accordingly kept affordable. Also it is easily accessible to all categories. Price range starts from Rs. 5 to Rs. 20 in different sizes. Cadbury Dairy Milk fruit and nut starts from Rs. 30. Dairy Milk Silk is a premium brand and thus the price of it is little higher that is Rs. 50. COMPETITOR’S ANALYSIS In Indian Market, the main players in the confectionery market are Cadbury, Nestle, Candico, ITC and Parle. Let us see the competitors of Cadbury Dairy Milk in detail below Company Founded in Brand Portfolio Kraft Foods 1903 Cadbury Dairy Milk Variants, Eclairs, Bourn vita etc†¦ Nestle 1860 Kitkat, Smarties Ferrero 1940 Rocher, Raffaelo, Nutella Amul 1945 Milk Chocolate, Fruit and Nut chocolate Candico 1997 Loco Poco Gum, Big Bubble ITC 2002(Confectionery Segment) Minto and Candy man Parle 1929 Melody, Mango Bite, Poppins, Kismi, Orange Candy POINT OF PARITY (POP) POINT OF DIFFERENCE (POD) POP’s POD’s OF CADBURY DAIRY MILK Point of Parity Point of Difference Chocolate manufacturing Legacy Goodwill Variants such as Fruit Nut, Dark Chocolate Emotional connect with customers Constant innovation in ads Generic name in Indian chocolate market Good quality products Campaigns targeting from kids to adults Association with milk Excellent distribution systems 2 Layer packaging Dairy Milk is the only one chocolate which says that in occasions also it can be used as sweet. BRAND EXPLORATORY Customer Knowledge Cadbury dairy Milk has been trying to get out of the image of† Just another chocolate† and become something special in the minds of the people. They have also been trying to position themselves as chocolates for all age groups and not just kids. The campaign has successfully created a picture in the mind of the customers that Cadbury is not just a chocolate but means of celebrations. Sources of Brand Equity There are two main sources of Brand Equity and they are: Based on various search results, Cadbury’s Dairy Milk not only enjoys high level of Brand Awareness but unaided Brand Recall. This level of recall is generated when Dairy Milk enjoys The Top of the Mind Effect. The Brand image of Cadbury Dairy Milk plays an important role in building the Brand Equity of Dairy Milk through the medium of unique brand associations. Right from Kuch Meetha Ho Jaye campaign to the recent Shubh Aarambh, Dairy Milk has managed to create strong, unique, and favorable brand associations in the minds of the consumers which is commendable. Brand Recall and Brand image are the strong supports that Dairy Milk has with its all time availability and attractive packaging which only adds to the Brand associations for the Dairy Milk and help build its Brand Equity. Two more important sources of Brand Equity are: \ BRAND AMBASSADORS As we know that previously Dairy Milk was only considered as Chocolate, but their new campaign has changed this perception of consumers. As discussed above now Dairy Milk is considered as Traditional sweet of Indian culture(Mithai) which people give to their near and dear ones on the occasions and now they use Dairy Milk as sweet(Mithai). Brand Ambassador chosen for Dairy Milk is none other than Megastar Amitabh Bacchhan. He endorsed the brand so successfully that everyone loved the brand much more than they did. The endorsement has successfully captured the Indian festivals like Rakshabandhan, Diwali, Wedding, Birthdays etc†¦ Now people give Dairy Milk as token of love, care and affection to their friends and family. DAIRY MILK MENTAL MAP These three form the mental map of Dairy Milk which associates with them the different aspects. Let us see them in detail: CBBE MODEL BRAND MANTRA OF DAIRY MILK SWOT ANALYSIS Strength Weakness Dairy milk is owned by Cadbury which is a globally established brand name known for its manufacturing competency and leadership in innovation. The recent acquisition of Cadbury by Kraft Foods may result in somewhat negative effect on the brand. Dairy Milk has been able to establish a clear and consistent Brand Image over the years. Dairy Milk is somewhat lacking in other emerging markets. It has strong command over its brand image in India and Europe But other places it is lacking. It offers quality product with innovations with crafted communication campaign Certain segment feel that price of Dairy Milk is high and compared to that Amul Milk chocolate is preferred. Dairy Milk has huge command over its distribution network spanning across India. Dairy Milk also enjoys a great Brand Recall value when comes to chocolates with Milk. Threats Opportunities Increasing competition from international brands is biggest threat to Dairy Milk To introduce sugar free category is biggest opportunity for Dairy Milk. Highly price sensitive nature of the industry. Dairy Milk can innovate more by bringing international flavors so that is also gets an opportunity to compete with this threat as well. BRAND STRATEGIES The marketing strategy that a business uses must reflect the objectives of the business as a whole. These strategies must therefore be consistent with the wider corporate objectives of the organization. Strategies are likely to be influenced by the attitudes of decision makers towards matters such as the desirability of risk and change. Such attitudes are influenced not only by the environment within which a business operates but also by the views of Managers and Directors and the culture of business itself. External influences also play a major role in any products advertising, its position in the market. They range from consumers to press and media, and also health and safety laws. PEST Analysis will more clearly throw light on external environment and global factors that may affect Dairy Milk’s Business. This will give a quick and visual representation of the external pressures facing the business and their possible constraints on strategy. PEST means: Political Factors Cadbury at the time of finalizing any marketing strategy will have to think of different political factors regionally, nationally and internationally.

Saturday, November 2, 2019

Presentaion on the country Syria Essay Example | Topics and Well Written Essays - 1000 words

Presentaion on the country Syria - Essay Example It is currently the liturgical language of many Syrian Christian denominations. However, most educated Syrians also speak French and English. The indigenous Christian Western-Aramaic speakers as well as Assyrians make up roughly 400,000 people. Most of them speak the Western Neo-Aramaic language. As for the deaf community, the sign language is used. Traditionally, men wear long gowns and women wear a long robe that only leaves their feet and hands exposed (Antoun 89). These dresses show little of the human skins something which is considered respectable. Music: Syria is one of the earliest centers of Christian hymnody and continues to be the liturgical music of various Syrian Christians. Damascus is among the Arab world centers for artistic innovation, particularly in the field of classical Arab music. Prominent musicians such as Asmahan, Lena Chamamyan, and Farid al-Atrash all come from Damascus (Salamandra 104). Aleppo city is known for its muwashshah; a form of Andalous poetry (Antoun 45). The muwashshah was popularized by stars like Sabah Fakri. It comprises of 5 stanzas that alternate in refrain with a running rhyme. Dance: As cited by Salamandra (103), the Syrian traditional art is manifested in dances like the Dabkeh, al-Samah, and sword dance. The Dabkeh is the national dance of Syria. It involves both line dancing and circle dance. It is commonly performed at weddings and other festivities. The lines usually form from right to left. The Dabkeh and al Samah are also peformed in child’s birth and marriage ceremonies. Food: Core element in parties, weddings, and other festivities. The main dish is the Syrian cuisine. It is rich and varied in its ingredients. It comprises of Kibbeh, fattoish, tabbouleh, hummus, labneh, shanklish, sujuk, baklava, and pastrirma. Manoushi bread is the number one snack food all around Syria. Tea is the ever-present drink and is usually taken with the Manoushi bread in

Thursday, October 31, 2019

Review the Capstone case Simon and Schuster, Inc. v. New York State Essay

Review the Capstone case Simon and Schuster, Inc. v. New York State Crime Victims Board on pages 412-417 of your textbook. Brief - Essay Example The Board then holds the money for satisfaction of all claims by the victims and creditors of the criminal or accused. The Court held that such a law smacks of First Amendment breach because of state imposition on content-based speech, which parallels the discriminatory tax law declared unconstitutional in Arkansas Writers’ Project Inc v Ragland 481 US 221. Two elements can be gleaned from the SC declaration of First Amendment inconsistency: the singling out of income from expressive activity, and; the singling out of â€Å"works with specified content.† This constitutional defect could have been overcome by compelling state interest, according to the SC, such as compensating victims of crimes or precluding criminals from profiting from their crimes. The disputed law, however, does not further state interest because there is no rationale in limiting its application to income derived from contents-based story of the criminal or accused. To allow the law entails placing i n its ambit a potentially large number of works such as the Confession of St. Augustine where he narrated stealing pears from his neighbor’s yard as an instance of moral weakness.

Tuesday, October 29, 2019

Inevitably is always better than large organizations at making Essay

Inevitably is always better than large organizations at making innovations - Essay Example Small and medium-sized enterprises are business enterprises which are seen to variously exhibit some common characteristics, which are; these business enterprises employ an average of up to about 250 employees, they have an annual turnover that is approximated as being not more than ?50 million and their management is also seen as largely independent in addition to being free from any outside control and influence in taking various principal decisions (European Commission, 2013). The Role/Place of Small and Medium-sized Business Enterprises in the Economy SMEs are important to all the different economies in the world, this is especially so to those economies found in the world’s developing countries that happen to be struggling with income distribution and employment challenges. During the 1980s, the total turnover, stocks and employment in most of the firms operating a wide range of business activities and services in the United Kingdom was seen to record spectacular growth. This growth was witnessed in the operations of all the large and small business enterprises. ... The number of SMEs within the United Kingdom has managed to record rapid growth during both the 1980s and the 1990s with estimates showing growth margins of from 57 percent to an average of 67 percent (Analoui and Karami 2003). The United Kingdom’s over 3.7 million SMEs are approximated to account for about 40 percent of the country’s total GDP. The SMEs also generate an annual turn over of about one trillion pounds in addition to employing approximately over 12 million people. Of the 2.3 million jobs that were created in the United Kingdom by the formation of new businesses between the years ranging from 1995 through to 1999, SMEs account for about 85 percent of this figure while they also accounted for more than 50 percent of the more than 3.5 million jobs that were gained as companies in the United Kingdom expanded over the same time period (Analoui and Karami 2003). Despite small firms accounting for such a large portion of the country’s GDP, Britain has been show to be relatively poorly endowed with small firms (Nelson, 1993). As a consequence of the trend showing constant growth of SME’s both in the United Kingdom and the world, SMEs have been noted as accounting for an average of about 99 percent of all businesses in the United Kingdom, while globally, SMEs are seen to account for business enterprise in excess of 99 percent of all the businesses that have been established. It is due to this that SME are considered to be the largest contributor to both the gross domestic product and the employment rates of all the countries in the world (Nwankwo and Gbadamosi, 2010). In order for SMEs to compete successfully and improve their chances of

Sunday, October 27, 2019

Efficacy of Oral Exfoliative Cytology in Diabetes Mellitus

Efficacy of Oral Exfoliative Cytology in Diabetes Mellitus EFFICACY OF ORAL EXFOLIATIVE CYTOLOGY IN DIABETES MELLITUS PATIENTS-A LIGHT MICROSCOPIC CONFOCAL MICROSCOPIC STUDY Abstract Introduction: Diabetes Mellitus has become a global problem. By monitoring the health status of these individuals, diabetic complications leading to morbidity can be prevented. Aim: We aimed to analyze alterations in the morphology and cytomorphometry of buccal epithelial cells of Type 2 Diabetes Mellitus patients using oral exfoliative cytology technique and determine its importance in public health screening, diagnosis and monitoring of diabetes mellitus. Material Methods: The study was carried out in 100 Type 2 Diabetes Mellitus patients and 30 healthy individuals. Smears were taken from the right buccal mucosa and stained by the Papanicolaou technique. Staining with Acridine orange was carried out to view qualitative changes with confocal laser scanning microscope (LSM-510 Meta).The cytomorphometry was evaluated using IMAGE PRO PLUS 5.5 software with Evolution L.C camera. All findings were statistically analyzed. Results: The results showed that with increase in fasting plasma glucose levels, there is significant increase in nuclear area, decrease in cytoplasmic area, and increase in nuclear cytoplasmic ratio (P Conclusion: In the present study, we found significant alterations in the cytomorphometry and cytomorphology of buccal epithelial cells of Type 2 Diabetes Mellitus patients. This study supports and extends the view that these cellular changes can alert the clinician to the possibility of diabetes and aid in monitoring of diabetes throughout the lifetime of the patient. Keywords: Confocal laser scanning microscope; Cytomorphometry; Diabetes mellitus; Oral exfoliative cytology. Introduction Diabetes mellitus (DM) is not a single disease entity but rather a group of metabolic disorders sharing the common underlying feature of hyperglycemia. Hyperglycemia results from defects in insulin secretion, insulin action or both. The chronic hyperglycemia and resultant metabolic deregulation of carbohydrate, fat and protein may be associated with secondary damage in multiple organ systems, especially the kidneys, eyes, nerves and blood vessels.1Recent estimates indicate that the number of people with DM in 2010 is 285 million and is expected to be 438 million in 2030. The global prevalence rate is 6.6% in 2010 and is expected to rise to 7.8% in 2030.2 India leads the world with largest number of diabetic subjects earning the dubious distinction of being termed the â€Å"diabetes capital of the world†. According to the Diabetes Atlas 2009 published by the International Diabetes Federation, the total number of people with diabetes in India is 50.8 million and is expected to rise to 87 million in 2030.3 It can no longer be considered a disease of affluent nation alone, it has become a global problem, a major epidemic of the twentieth century, and one which shows no sign of abating. 3 DM is the leading cause of end-stage renal disease, adult-onset blindness and traumatic lower extremity amputations. The prevalence of DM is increasing sharply in the developing world as more people adopt a sedentary lifestyle, with India and China being the largest contributors to the world’s diabetic load.2 Oral Exfoliative cytology is a relatively simple and non-invasive clinical technique which has the potential to be developed as a routine investigation for screening of DM. It can be used chair-side during routine dental examination.4The various alterations in the cytomorphology of the oral mucosa in diabetes and characterization of these changes give clinicians a more accurate image of what really happens during diabetes. So in our study, the cytomorphometric and cytomorphologic changes were compared according to the different glucose levels of diabetes. In addition to light microscope, we used confocal laser scanning microscope, to ascertain the various cytomorphologic changes seen under light microscope. It is possible that the degree of cellular change depends on the progression of diabetes. Hence the present study was undertaken as this research area has received little attention to date. Materials Methods Selection of subjects: The study was carried out in Type 2 DM patients attending the diabetic outpatient department of General Medicine of Sri Ramachandra University, Chennai, India. These patients were under regular monitoring of blood sugar levels and subsequent treatment. The experimental group included 100 Type 2 DM patients and the control group consisted of 30 healthy individuals free of any systemic diseases with clinically normal oral mucosa. Study groups: The entire study sample was grouped for statistical analysis, based on the recent Fasting Plasma Glucose (FPG) levels as follows: Group I: FPG 110-150mg/dl; Group II: FPG 150-200mg/dl; Group III: FPG >200mg/dl; Control: FPGExclusion criteria: Individuals with habit of tobacco use in any form, habitual alcohol intake, any other systemic illness, clinically evident nutritional deficiencies like anemia, presence of oral sepsis were excluded from the study. After selection of the patient, informed consent was obtained and the p rocedure was carried out. In addition, the biochemical hematological measurements were carried out to exclude anemia other systemic disease. Smear collection and preparation: Patients were asked to rinse their mouth to remove any debris. Following this, with a gentle scraping motion, cells were scraped from clinically normal appearing right buccal mucosa. The scrapings were then evenly smeared onto the glass slide and immersed in 95% isopropyl alcohol in a coplin jar, for half an hour. Staining technique: Smears from all the samples were stained by the Papanicolaou technique (PAP).For few samples two smears were taken from the same site, one stained using PAP and other using Acridine orange(AO), a fluorescent dye, to view with confocal laser scanning microscope. In cases with very high plasma glucose levels smear was stained with Periodic Acid Schiff (PAS) technique to assess presence of candida. Cytomorphometric assessment: The cytomorphometric analysis was done using IMAGE PRO PLUS 5.5 software with Evolution L.C camera. In each of the PAP stained slide, ten fields were chosen by systematic sampling in a step wise manner, moving from left to right and then down and across in order to avoid measuring the same cells again. Cells with clearly defined cellular outlines were only chosen those that were clumped, overlapped or folded were excluded for analysis. The cells were projected on to the monitor via the camera at 40x magnification and images were captured. In the software main menu, the function ‘Measurement mode’ was selected and the icon specifying ‘polygon’ was enabled to analyze the area of interest. The nuclear area (NA) and cytoplasmic area (CA) were obtained by drawing around the nuclear and cell boundaries using the cursor. The areas were recorded in square microns. The nuclear cytoplasmic ratio (N/C) was calculated for all the cells. The various parameters calculated were by the Image analysis software thereby reducing the subjective error. Cytomorphologic assessment: The PAP PAS stained slides were viewed under light microscope whereas the AO stained slides were viewed under confocal laser scanning microscope (LSM-510 meta).Morphologic assessment included inflammatory component, cell degeneration, micronuclei, binucleation, intracytoplasmic inclusion, candida, keratinization, intracytoplasmic microorganisms any other changes. Results On comparison of the cytomorphometry between the various study groups, the results showed a significant increase in the NA N/C ratio (p Discussion DM has become a global problem. It is not a disease but a metabolic disorder. Early detection and subsequent monitoring of this disorder will definitely improve the health of individuals suffering from diabetes. By monitoring the health status of the individuals, diabetic complications leading to morbidity can be prevented, thus producing a healthy society. In the present study we aimed to analyze alterations in the morphology and cytomorphometry of buccal mucosal cells of Type 2 diabetics using exfoliative cytology technique and determine its importance in public health screening and monitoring of DM. The study showed a significant steady increase in NA with increase in blood sugar level (Figure1) from control group (Mean NA-51.03 µm2) to the diabetic Group III (Mean NA-81.21  µm2). This finding concurs with other previously reported studies who reported a significant increase in NA in diabetic patients.5-7 However all these studies did not categorize the patients based on the blood glucose levels. Similar studies using cytomorphometry have been done to analyze the effect of alcohol, tobacco, radiotherapy on buccal mucosa. 8-12 Nucleus contains the genomic DNA, histones and several proteins. The nuclear size can therefore be altered by change in the content of DNA or proteins. There is usually twice as much protein as DNA in a nucleus.13 Hyperglycemia induces a compensatory increase in insulin secretion which in turn causes increase in protein formation. Insulin has several mitogenic functions, including initiation of DNA synthesis in certain cells. These may account for the i ncrease in NA seen in diabetes patients.14 Our study revealed a decrease in CA with increase in blood sugar level i.e.GroupIII mean CA was 2270.63  µm 2 and control mean CA was 2771.6  µm2 (Figure1). This finding is contradictory to studies by Alberti et al 5 and Shareef et al6 who found that CA did not show any significant difference in diabetics and Hassan et al7 who reported a significant increase in CA. However this finding concurs with Prasad et al15 who reported increase in cell diameter and cytoplasmic diameter with increase in glycemic status. Ogden et al10 have reported a similar reduction in cell diameter in patients with habit of alcoholism. The reduction in CA in our study could be due to the dehydrated condition of the diabetics. Increased blood glucose causes dehydration, polyuria polydipsia, intracellular extracellular dehydration. Glucose does not diffuse easily through the pores of the cell membrane causing an increase in osmotic pressure. This increase in osmotic pressure in extracellular fluid causes o smotic transfer of water out of the cells explaining the reduction in CA.16 The comparison of N/C ratio between control and experiment groups showed a steady increase in N/C ratio (from Control-0.0188 to Group III-0.0369) with increasing blood glucose levels(Figure1) .This may be due to a real increase in NA and decrease in CA in diabetic patients, rather than just a deviation from normal. This finding concurs with Rivera et al17 and Prasad et al15 who also reported increase in N/C ratio. In the qualitative changes we found that micronuclei (MN) was present in 44 cases which was statistically significant (p=0.018). MN are known biomarkers of genome damage and has been studied in buccal cell systems. They provide a convenient and reliable index of both chromosome breakage and chromosome loss.MN is found in cells that have completed nuclear division.MN was judged according to criteria by Tolbert et al. 18 Another biomarker of genome damage is nuclear bud formation which was also visualized but not statistically analyzed.16 The nuclear bud has the same morphology and staining properties as the nucleus, however, its diameter may range from a half to a quarter of that of the main nucleus. Hyperglycemia results in formation of Advanced Glycation End products (AGE), endothelial nitric oxide synthase uncoupling, activation of protein kinase C activation of polyol pathway. This in turn causes activation of reactive oxygen species which results in induction of oxidative stress . Oxidative stress is an imbalance between the production of reactive oxygen species and the biological systems ability to readily detoxify the reactive intermediates or to repair the resulting damage. The effects of oxidative stress depend upon the size of these changes, wherein a cell can overcome small perturbations and regain its original state. However, more severe oxidative stress can cause cell death and even moderate oxidation can trigger apoptosis, while more intense stresses may cause necrosis. Oxidative stress has been found to cause genomic damage in DM. 19 This supports the observation of MN in diabetic patients. Few other studies also showed increase in MN in lymphocyte cultures of type 2 diabetics.20, 21 This is the first reported study in which an attempt has been made to study qualitative changes of buccal smear using confocal microscopy. The use of fluorescence dye (Acridine Orange) and visualization under confocal laser scanning microscope enhanced the demonstration of nuclei and micronuclei. They also helped to avoid false positive results. Statistical analysis revealed that cell degeneration was present in 44 cases out of 100 cases. It was statistically significant (p=0.05) implying that increase in blood glucose level leads to oxidative stress and showed increase in degeneration and necrosis. The various qualitative changes included karyorrhexis, pyknosis, apoptosis chromatin abnormalities. Previous studies by Alberti et al5 Shareef et al6 also demonstrated qualitative changes of karyorrhexis. Another significant qualitative change found was the presence of keratinization. This finding is in accordance with an earlier study by Zimmermann et al22 who stated that endocrine dis orders like DM had increased keratinized cell count in the buccal mucosa. The increase in this keratinization may be a compensation for decreased salivary flow.5 Binucleation was present in 45 cases out of 100 but showed no statistically significant result. The significance of these binucleate cells is unknown, but they are probably indicative of failed cytokinesis following the last nuclear division in the basal cell layer. Studies by Alberti et al5 and Shareef et al6 also showed similar findings of binucleation. Increased number of polymorphonuclear leukocytes was observed in the experiment group than chronic inflammatory cells. Increase in inflammation could be due to decreased salivary flow found in diabetics owing to hypofunction of the salivary glands. Hassan et al7 in their study found that incidence of inflammation was higher in diabetic smears. Figure2 Figure3 shows the various qualitative changes viewed under light microscope and confocal microscope. Conclusion: From our study, we could conclude that diabetes produces significant alterations in the cytomorphometry and cytomorphology of buccal epithelial cells. The use of confocal laser scanning microscopy demonstrated qualitative changes with higher resolution and clarity and helped in reducing the possibility of recording false positive and/or false negative observations. Clinical significance: Exfoliative cytology is helpful in diabetic patients who have aversion and fear to needle pricks as it is painless and can be carried out regularly .The minimal time and ease of the procedure is beneficial in mass screening and public health awareness programme. They also aid in monitoring of diabetes mellitus throughout the lifetime of the patient, thereby decreasing the morbidity and preventing long term complications. Acknowledgements Authors would like to thank the Central Research Facility Department of General Medicine of Sri Ramachandra University, Chennai. We would also like to thank the lab assistant Department of Oral pathology and statistician for their valuable help in the study. No conflict of interest. No source of funding.